# Gut GvHD

**URL:** <https://patientforum.anthonynolan.org/t/gut-gvhd/404>\
**Category:** Long-term recovery\
**Created:** [February 3, 2019, 10:26am UTC](https://patientforum.anthonynolan.org/t/gut-gvhd/404 "2019-02-03T10:26:57Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![Gem03](https://avatars.discourse-cdn.com/v4/letter/g/a87d85/32.png) [@Gem03](https://patientforum.anthonynolan.org/u/Gem03)\
**Post date:** [February 3, 2019, 10:26am UTC](https://patientforum.anthonynolan.org/t/gut-gvhd/404/1 "2019-02-03T10:26:57Z")

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Hi, I am just around the 100 day mark and have been doing really well over all. My blood counts are good, so far I’ve not had any infections or readmission to hospital. I have had skin GvHD but this was only minor and has cleared up. All in all I’ve been feeling very lucky with how things have gone but… I have had, however, persistent gut GvHD which has been treated with prednisone initially. This sorted the sickness I was feeling but the lower gut has continued to have issues (very windy and diarrhoea). I have now been put on Budesonide. Has anyone else had issues with gut GvHD? How long does Budesonide take to have an effect? Is this likely to be a permanent thing?

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**Author:** ![SueP](https://avatars.discourse-cdn.com/v4/letter/s/3bc359/32.png) [@SueP](https://patientforum.anthonynolan.org/u/SueP)\
**Post date:** [February 4, 2019, 5:54pm UTC](https://patientforum.anthonynolan.org/t/gut-gvhd/404/2 "2019-02-04T17:54:59Z")

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Hi,

I’m one of the community champions on this forum. I had my transplant five years ago. I didn’t have many complications but the lower gut problems lasted longer than the others. The symptoms were the same as yours. They obviously weren’t as bad as I didn’t need specific medication but I certainly wasn’t happy being too far away from a toilet for a long time! It’s difficult to remember how long it lasted but I would guess up to six months. I’m back to normal now.  
I hope this helps,  
Very best wishes,  
Sue

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**Author:** ![greg777](https://avatars.discourse-cdn.com/v4/letter/g/c5a1d2/32.png) [@greg777](https://patientforum.anthonynolan.org/u/greg777)\
**Post date:** [February 4, 2019, 9:56pm UTC](https://patientforum.anthonynolan.org/t/gut-gvhd/404/3 "2019-02-04T21:56:16Z")

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Hi Gem,  
Really sorry to read about your current problems. I had gut GvHD problems from around Day 50. Steroids and budesonide didn’t do much for me and I had to have mesenchymal stem cells to sort things out. It was a tough period as I had to go nil by mouth with TPN for about a month. Things sorted themselves out after about 8 months and now I am 3 years post and don’t have any major ongoing problems. The doctors said to me that sometimes the body just needs time to sort itself out. I didn’t believe them at the time but in my case they were right. It is a major procedure we have all gone through after all. Really hoping you find the budesonide does the trick soon.  
All the best  
Greg