# Top up

**URL:** <https://patientforum.anthonynolan.org/t/top-up/400>\
**Category:** Long-term recovery\
**Created:** [January 16, 2019, 12:21pm UTC](https://patientforum.anthonynolan.org/t/top-up/400 "2019-01-16T12:21:25Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Lindsaylou](https://avatars.discourse-cdn.com/v4/letter/l/838e76/32.png) [@Lindsaylou](https://patientforum.anthonynolan.org/u/Lindsaylou)\
**Post date:** [January 16, 2019, 12:21pm UTC](https://patientforum.anthonynolan.org/t/top-up/400/1 "2019-01-16T12:21:25Z")

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Hi,  
My husband is on about day 120 and his cherism levels have gone down to 78%, and he has now got to have a top up donar cells. Has anyone else had to have this done, I understand he could be in danger of GHVD as well  
Thanks lindsay

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**Author:** ![Bernie](https://avatars.discourse-cdn.com/v4/letter/b/f19dbf/32.png) [@Bernie](https://patientforum.anthonynolan.org/u/Bernie)\
**Post date:** [January 17, 2019, 3:50pm UTC](https://patientforum.anthonynolan.org/t/top-up/400/2 "2019-01-17T15:50:12Z")

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Hi Lindsay  
Hearing your husband needs a top up can be daunting but I don’t think it’s unusual.  
I had mine 8 months post transplant as my chimerism had dropped to 55%. I only needed one top up, though I was told sometimes more are needed.  
I was warned about possible GVHD but I didn’t have any issues at the time. I was also warned to carry on being cautious due to the increased risk of infection but to be honest I was still on high alert if anyone so much as cleared their throat around me at that time anyway.  
My chimerism has been at 98% + since then and I’ll be two years post transplant in February. I have very mild gut GVHD at the minute but it’s manageable.  
Good luck  
Bernie xx